BIOMARKER SIGNATURES FOR PREDICTING DRUG RESPONSE IN HODKIN'S LYMPHOMA

摘要

The present invention provides an in vitro method for determining the responsiveness of an individual with Hodgkin's lymphoma to chemotherapeutic drug treatment, the method comprising the steps of providing a protein or mRNA sample from a lymph node of the individual to be tested and then determining the presence and/or amount in the sample of at least two proteins selected from the group identified in Table A, and/or of mRNA encoding the same, wherein the presence and/or amount in the sample of the proteins selected from the group defined in Table A, or of the mRNA encoding the same, is indicative of the responsiveness of the individual with Hodgkin's lymphoma to chemotherapeutic drug treatment. The invention further provides arrays and kits for use in the same.