发明名称 RETROVIRAL TRANSDUCTION USING POLOXAMERS
摘要 The present invention relates to a method for transducing a target cell, the method comprising the step of contacting a target cell with a retroviral vector and a poloxamer having a molecular weight of 12.8 kDa to about 15 kDa. Further, the invention relates to the use of a poloxamer as defined herein, optionally in combination with a polycationic substance as defined herein, for transducing a target cell with a retroviral vector and a kit comprising a retroviral vector, a poloxamer as defined herein and, optionally, instructions for use.
申请公布号 EP2820138(A1) 申请公布日期 2015.01.07
申请号 EP20130706283 申请日期 2013.02.28
申请人 HELMHOLTZ ZENTRUM MÜNCHEN - DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH);SIRION BIOTECH GMBH 发明人 ANASTASOV, NATASA;HÖFIG, INES;THIRION, CHRISTIAN
分类号 C12N15/867;A61K48/00 主分类号 C12N15/867
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