发明名称 |
イントロンRNAを用いたヒト胚性幹様細胞の生成 |
摘要 |
The present invention relates to a method and composition for generating a non-naturally occurring intron and its components capable of being processed into small hairpin RNA (shRNA) and/or microRNA (miRNA) molecules by skin cells and thus inducing specific gene silencing effects on skin pigment-related genes and/or aging-causing genes in the cells. The gene silencing effects so obtained are not only useful for lightening and whitening skin colors but also useful for suppressing unwanted aging gene activities in skins. |
申请公布号 |
JP5649967(B2) |
申请公布日期 |
2015.01.07 |
申请号 |
JP20100526976 |
申请日期 |
2008.03.10 |
申请人 |
リン、シー−ランLIN,Shi−Lung;イン、シャオ ヤオYING,Shao Yao;ウー、デイビッド ティーエスWU,David TS |
发明人 |
リン、シー−ラン;イン、シャオ ヤオ;ウー、デイビッド ティーエス |
分类号 |
C12N15/09;C12N5/10;C12N15/11;C12N15/113 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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