发明名称 |
COMBINATION OF A NSAID AND A PDE-4 INHIBITOR |
摘要 |
<p>The invention relates to the combined use of a PDE4 inhibitor and a conventional NSAID in the treatment of an inflammatory disease and/or an inflammation-associated disorder while minimizing gastrointestinal side effects, such as gastric erosions and ulcer, which are frequently associated with the use of conventional NSAIDs. A preferred PDE 4 inhibitor for this combination is roflumilast or a derivative thereof. A preferred conventional NSAID for this combination is diclofenac or a derivative thereof.</p> |
申请公布号 |
SI1429807(T1) |
申请公布日期 |
2007.08.31 |
申请号 |
SI20020030534T |
申请日期 |
2002.09.17 |
申请人 |
NYCOMED GMBH |
发明人 |
KLEIN THOMAS;KLEY HANS-PETER;HATZELMANN ARMIN;ELTZE MANFRID |
分类号 |
A61K45/06;A61K;A61K31/196;A61K31/40;A61K31/4015;A61K31/44;A61K31/4409;A61K31/4709;A61K31/513;A61K31/522;A61P;A61P1/04;A61P29/00;A61P43/00 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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