发明名称 |
Chirale oxazole-arylpropionic acid derivatives and their use as PPAR agonists |
摘要 |
Disclosed are chirale oxazole-arylpropionic acid derivatives of formula (I), pharmaceutically acceptable salts and esters thereof, and their use as PPAR agonists, wherein R1 to R6 and n are as defined in the specification. These compounds are useful for the treatment and/or prevention of diseases such as type II diabetes, which are modulated by PPARalpha and/or PPARgamma agonists.
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申请公布号 |
NZ538465(A) |
申请公布日期 |
2007.08.31 |
申请号 |
NZ20030538465 |
申请日期 |
2003.10.06 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BINGGELI, ALFRED;BOEHRINGER, MARKUS;GRETHER, UWE;HILPERT, HANS;HIRTH, GEORGES;MAERKI, HANS-PETER;MEYER, MARKUS;MOHR, PETER;RICKLIN, FABIENNE |
分类号 |
A61K31/421;A61P3/10;C07D263/32;(IPC1-7):C07D263/32 |
主分类号 |
A61K31/421 |
代理机构 |
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