发明名称 Chirale oxazole-arylpropionic acid derivatives and their use as PPAR agonists
摘要 Disclosed are chirale oxazole-arylpropionic acid derivatives of formula (I), pharmaceutically acceptable salts and esters thereof, and their use as PPAR agonists, wherein R1 to R6 and n are as defined in the specification. These compounds are useful for the treatment and/or prevention of diseases such as type II diabetes, which are modulated by PPARalpha and/or PPARgamma agonists.
申请公布号 NZ538465(A) 申请公布日期 2007.08.31
申请号 NZ20030538465 申请日期 2003.10.06
申请人 F. HOFFMANN-LA ROCHE AG 发明人 BINGGELI, ALFRED;BOEHRINGER, MARKUS;GRETHER, UWE;HILPERT, HANS;HIRTH, GEORGES;MAERKI, HANS-PETER;MEYER, MARKUS;MOHR, PETER;RICKLIN, FABIENNE
分类号 A61K31/421;A61P3/10;C07D263/32;(IPC1-7):C07D263/32 主分类号 A61K31/421
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