发明名称 |
INTERLEUKIN-3 POLYPEPTIDE CONJUGATES THEIR USES |
摘要 |
<p>The disclosure provides methods for targeting interleukin-3 receptor-expressing cells, particularly inhibiting the growth of such cells by using an interleukin-3 (IL-3) variant conjugated to a toxin that will affect cells expressing the interleukin-3 receptor. Further disclosed are interleukin-3 (IL-3) variants comprising one or more non-naturally encoded amino acids, and the structures of non-naturally encoded amino acids.</p> |
申请公布号 |
EP2820030(A1) |
申请公布日期 |
2015.01.07 |
申请号 |
EP20130755082 |
申请日期 |
2013.02.28 |
申请人 |
AMBRX, INC. |
发明人 |
NELSON, MELANIE;EATON, KRISTIN, S. |
分类号 |
C07K1/00;A61K38/00;A61K45/00;C12P21/04 |
主分类号 |
C07K1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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