发明名称 |
PREPARATION OF MOLECULAR IMPRINTED POLYMERS BY CROSS-LINKING |
摘要 |
<p>Provided is an improved method for preparation of insoluble molecular imprinted polymers (MIPs), the method comprising: a) providing soluble or semi-soluble MIPs that 1) substantially all bind template agents and 2) have sizes which enable their separation in a chromatographic step utilizing packed bed chromatography, b) cross-linking the template agent binding soluble MIPs provided in step a so as to obtain insoluble template agent binding MIPs, and c) optionally isolating, concentrating or purifying the MIPs obtained by the cross-linking in step b. In an interesting embodiment, step a includes an affinity purification procedure, which ensures that the MIPs provided in step a are indeed all binders of the template.</p> |
申请公布号 |
EP2819778(A1) |
申请公布日期 |
2015.01.07 |
申请号 |
EP20120708277 |
申请日期 |
2012.02.28 |
申请人 |
MIPSALUS APS |
发明人 |
GREGORIUS, KLAUS;NICHOLLS, IAN, ALAN;KROGH, NICOLAS, OTTO |
分类号 |
B01J20/26;B01D15/38;B82Y40/00;C08F8/00;C08J3/24 |
主分类号 |
B01J20/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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