发明名称 |
PEGYLATED ANALOGUE PROTEIN OF CANINE URATE OXIDASE, PREPARATION METHOD AND USE THEREOF |
摘要 |
<p>Provided are a PEGylated analogue protein of canine urate oxidase, preparation method and use thereof. The analogue protein of canine urate oxidase is a canine urate oxidase, or a chimeric protein comprising part of the amino acid sequence of a canine urate oxidase and part of the amino acid sequence of a human urate oxidase, or a mutant protein thereof. The PEGylated analogue protein of canine urate oxidase and pharmaceutical compositions thereof according to the present invention can be used for the prevention and/or treatment of hyperuricemia and chronic gout.</p> |
申请公布号 |
EP2684950(A4) |
申请公布日期 |
2015.01.07 |
申请号 |
EP20120747724 |
申请日期 |
2012.02.14 |
申请人 |
CHONGQING FAGEN BIOMEDICAL INC. |
发明人 |
ZHANG, CHUN;FAN, KAI;MA, XUEFENG;YANG, LI;HU, CHUNLAN;LUO, HUA;MEI, XIANG |
分类号 |
C12N9/06;A61K38/44;A61K47/48;A61P13/12;A61P19/02;A61P19/06 |
主分类号 |
C12N9/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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