高活性アントラサイクリン系抗生物質の誘導体、該誘導体の製造及び応用

摘要

Anthracycline antibiotic derivatives with anticancer activity, i.e. the compounds of formula (I). The present anthracycline antibiotic derivatives has the same activity as or higher activity than that of the known medicaments such as doxorubicin, daunorubicin in the cellular level and at the same time the present derivatives have better tolerance than doxorubicin in animal body.