| 发明名称 |
Polycarbonates bearing pendant primary amines for medical applications |
| 摘要 |
An antimicrobial composition comprises an anionic drug and an amine polymer comprising a first repeat unit of formula (2):;
wherein a′ is an integer equal to 1 or 2, b′ is an integer equal to 1 or 2, and each R′ is an independent monovalent radical selected from the group consisting of hydrogen, methyl, ethyl, and combinations thereof. G′ is a divalent linking group selected from the group consisting of a single bond and groups comprising at least one carbon. X− is a negatively charged counterion. The drug and the amine polymer are bound by noncovalent interactions. |
| 申请公布号 |
US8926998(B2) |
申请公布日期 |
2015.01.06 |
| 申请号 |
US201213611116 |
申请日期 |
2012.09.12 |
| 申请人 |
International Business Machines Corporation;Agency For Science, Technology And Research |
发明人 |
Hedrick James L.;Venkataraman Shrinivas;Yang Yi Yan |
| 分类号 |
A01N25/00;A61K31/00;A61L33/00;B05D3/02 |
主分类号 |
A01N25/00 |
| 代理机构 |
|
代理人 |
Roberts Michael R. |
| 主权项 |
1. An antimicrobial composition, comprising:
an anionic drug; and an amine polymer comprising a first repeat unit of formula (2):wherein
a′ is an integer equal to 1 or 2, b′ is an integer equal to 1 or 2, each R′ is an independent monovalent radical selected from the group consisting of hydrogen, methyl, and ethyl, G′ is a divalent linking group comprising i) at least one carbon and ii) a nitrogen bonded to the backbone of the amine polymer, X− is a negatively charged counterion, and the drug and the amine polymer are bound by noncovalent interactions. |
| 地址 |
Armonk NY US |
