| 发明名称 |
Vaccine |
| 摘要 |
The present invention relates to the field of bacterial polysaccharide antigen vaccines. In particular, the present invention relates to bacterial polysaccharides conjugated to protein D from H. influenzae. |
| 申请公布号 |
US8926985(B2) |
申请公布日期 |
2015.01.06 |
| 申请号 |
US200912612988 |
申请日期 |
2009.11.05 |
| 申请人 |
GlaxoSmithKline Biologicals S A |
发明人 |
Capiau Carine;Deschamps Marguerite;Desmons Pierre Michel;Laferriere Craig Antonyjoseph;Poolman Jan;Prieels Jean-Paul |
| 分类号 |
A61K39/385;A61K39/116;A61K39/00;A61K39/02;A61K39/09;A61K39/102;A01N43/04;C07H1/00;A61K39/095;A61K39/155 |
主分类号 |
A61K39/385 |
| 代理机构 |
|
代理人 |
Bradney Alice P. |
| 主权项 |
1. A multivalent immunogenic composition comprising isolated capsular polysaccharides of at least four serotypes of Streptococcus pneumoniae, each of said isolated capsular polysaccharides conjugated to an isolated protein D from Haemophilus influenzae that lacks a leader peptide and the N-terminal cysteine and contains a T-helper epitope, wherein the protein D is not lipidated. |
| 地址 |
Rixensart BE |
