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1. A compound represented by the formula (1), a pharmacologically acceptable salt thereof, or a hydrate thereof: wherein R1 is selected from a nitro group, a hydroxy group, a halogen atom, a cyano group, a (C1-C4) alkyl group, a (C1-C4) alkoxy group, a (C2-C4) alkenyl group, a (C2-C4 alkynyl group, a —CO(C1-C4) alkyl group, a —S(O)a(C1-C4) alkyl group (wherein a is 0, 1, or 2), and a (C3-C6) cycloalkyl group, and R1 and R2 may each independently be substituted at their respective carbon atoms with one or more halogen atom(s), cyclopropyl group(s), cyclobutyl group(s), and/or (C1-C4) alkoxy group(s); R2 is selected from a hydrogen atom, a nitro group, a hydroxy group, a halogen atom, a cyano group, a (C1-C4) alkyl group, a (C1-C4) alkoxy group, a (C2-C4) alkenyl group, a (C2-C4) alkynyl group, a —CO(C1-C4) alkyl group, a —S(O)a(C1-C4) alkyl group (wherein a is 0, 1, or 2), and a (C3-C6) cycloalkyl group, and R1 and R2 may each independently be substituted at their respective carbon atoms with one or more halogen atom(s), cyclopropyl group(s), cyclobutyl group(s), and/or (C1-C4) alkoxy group(s); W represents a single bond, —O—, —NR5—, NR5CH2—, or —C(R6)(R7)—; ring A is a 1,3-azetidine; X represents a single bond, —O—, —NR8—, —C(R9)(R10—, —C(O)—, —S(O)p— (wherein p is an integer of 0, 1, or 2), —C(O)NR11—, —NR12C(O)—, —S(O)2NR13—, or —NR14S(O)2—; Y represents a single bond, a hydrocarbon ring group, or a heterocyclic ring group; R3 and R4 are each independently selected from the following substituents: the substituents are a hydrogen atom, a halogen atom, a nitro group, a cyano group, an oxo group, a hydroxy group, a trifluoromethoxy group, an amino group, a carboxy group, a carbamoyl group, a mercapto group, a sulfamoyl group, a sulfo group, a formyl group, an ureido group, a hydroxyiminomethyl group, a (C1-C4) alkoxyiminomethyl group, an N-hydroxyformamide group, a (C1-C4) alkylhydrazino group, a hydrazinocarbonyl group, an N-hydroxyethanimidoyl group, a (C1-C4) alkyl group, a (C2-C4) alkenyl group, a (C2-C4) alkynyl group, a (C1-C4) alkoxy group, —CO(C1-C4) alkyl, —OC(O)(C1-C4) alkyl, —NH(C1-C4) alkyl, —N[di(C1-C4) alkyl], —NHC(O)(C1-C4) alkyl, —C(O)NH(C1-C4) alkyl, —C(O)N[di(C1-C4) alkyl], —C(O)NH(C1-C4) alkoxy, —NHC(O)NH(C1-C4) alkyl, —NHC(O)N[di(C1-C4) alkyl], —C(O)N[(C1-C4) alkyl][(C1-C4) alkoxy], —S(O)a(C1-C4) alkyl (wherein a is 0, 1, or 2), —C(O)(C1-C4) alkoxy, —OC(O)(C1-C4) alkoxy, —NHC(O)(C1-C4) alkoxy, —S(O)2NH(C1-C4) alkyl, —S(O)2N[di(C1-C4) alkyl], —NHSO2(C1-C4) alkyl, —C(O)NHSO2(C1-C4) alkyl, —C(O)NHNH(C1-C4) alkyl, —C(O)NHN[di(C1-C4) alkyl], ═CH(C1-C4) alkyl, ═C[di(C1-C4) alkyl], ═N(C1-C4) alkoxy, ═NN[di(C1-C4) alkyl], —R15-hydrocarbon ring, and —R16-heterocyclic ring, and R3 and R4 may each independently be substituted with one or more R17 moiety/moieties; R5, R6, R7, R8, R9, R10, R11, R12, R13, and R14 each independently represent a hydrogen atom or a (C1-C4) alkyl group, wherein the (C1-C4) alkyl group may be substituted with R17; n is an integer of 0, 1, 2, 3, or 4, wherein a plurality of R3 moieties are the same or different; m is an integer of 0, 1, 2, 3, or 4, wherein a plurality of R4 moieties are the same or different; R17 is selected from an azide group, a halogen atom, a nitro group, a cyano group, an oxo group, a hydroxy group, a trifluoromethoxy group, an amino group, a carboxy group, a carbamoyl group, a mercapto group, a sulfamoyl group, a (C1-C4) alkyl group, a (C2-C4) alkenyl group, a (C2-C4) alkynyl group, a (C1-C4) alkoxy group, a —CO(C1-C4) alkyl group, a —OC(O)(C1-C4) alkyl group, —OC(O)(C1-C4) alkoxy, a —NH(C1-C4) alkyl group, a —N[di(C1-C4) alkyl] group, a —NHC(O)(C1-C4) alkyl group, —C(O)NH(C1-C4) alkyl, —C(O)N[di(C1-C4) alkyl], —C(O)NH(C1-C4) alkoxy, —NHC(O)NH(C1-C4) alkyl, —NHC(O)N[di(C1-C4) alkyl], —C(O)N[(C1-C4) alkyl][(C1-C4) alkoxy], —S(O)a(C1-C4) alkyl (wherein a is 0, 1, or 2), —C(O)(C1-C4) alkoxy, —S(O)2NH(C1-C4) alkyl, —S(O)2N[di(C1-C4) alkyl], —NHS(O)2(C1-C4) alkyl, —NHC(O)(C1-C4) alkoxy, ═CH(C1-C4) alkyl, ═C[di(C1-C4) alkyl], ═N(C1-C4) alkoxy, ═NN[di(C1-C4) alkyl], —R18-hydrocarbon ring, and —R19-heterocyclic ring, and R17 moieties may each independently be substituted with one or more R20 moiety/moieties; R15, R16, R18, and R19 are each independently selected from a single bond, a double bond, —C(R21)(R22)—, —O—, —N(R23)—, —C(O)—, —N(R24)C(O)—, —C(O)N(R25)—, —S(O)p— (wherein p is an integer of 0, 1, or 2), —S(O)2N(R26)—, —N(R27)S(O)2—, —O(CO)O—, —C(R28)═, and —N═, wherein R21, R22, R23, R24, R25, R26, R27, and R28 are each independently selected from a hydrogen atom and a (C1-C4) alkyl group; and R20 is selected from a halogen atom, a nitro group, a cyano group, an oxo group, a hydroxy group, a trifluoromethoxy group, a trifluoromethyl group, an amino group, a carboxy group, a carbamoyl group, a mercapto group, a sulfamoyl group, a methyl group, an ethyl group, a vinyl group, a methoxy group, an ethoxy group, an acetyl group, an acetoxy group, a methylamino group, an ethylamino group, a dimethylamino group, a diethylamino group, —N(methyl)(ethyl), —NHC(O)-methyl, —C(O)NH-methyl, —C(O)NH-ethyl, —C(O)N[di(methyl)], —C(O)N[di(ethyl)], —C(O)N[(methyl)(ethyl)], a methylthio group, an ethylthio group, —S(O)-methyl, —S(O)-ethyl, —S(O)2-methyl, —S(O)2-ethyl, a methoxycarbonyl group, an ethoxycarbonyl group, —S(O)2NH-methyl, —S(O)2NH-ethyl, —S(O)2N[di(methyl)], —S(O)2N[di(ethyl)], and —S(O)2N[(methyl)(ethyl)]. |
