发明名称 Method to increase the production of extracellular polymeric substances (EPS) in a <i>Acidithiobacillus ferrooxidans </i>culture by the inhibition of enzymes of tricarboxilic acid cycle
摘要 A method of increasing the production of extracellular polymeric substances (EPS) in an Acidithiobacillus ferrooxidans culture is disclosed. The method includes inhibiting an enzyme, such as citrate synthase, aconitase, or isocitrate dehydrogenase, in the tricarboxylic acid (TCA) cycle leading to alpha-ketoglutarate.
申请公布号 US8927246(B2) 申请公布日期 2015.01.06
申请号 US201113035336 申请日期 2011.02.25
申请人 Universidad de Chile;BioSigma S.A. 发明人 Maass Sepúlved Alejandro Eduardo;Moreno Cortéz Pablo Andrés;Budinich Abarca Marko Antonio;Parada Valdecantos Pilar Angélica;Padilla Iglesias Leandro Mauricio;Barreto Roa Marlen Nayibe
分类号 C12N9/99;C12P1/04;C12N1/38;C12P19/04 主分类号 C12N9/99
代理机构 Merchant &amp; Gould P.C. 代理人 Merchant &amp; Gould P.C.
主权项 1. A method to enhance extracellular polymeric substances (EPS) production in an Acidithiobacillus ferrooxidans culture employing ferrous sulfate as a nutrient source, the method comprising inhibiting tricarboxilic acid cycle (TCA) in the Acidithiobacillus ferrooxidans culture by contacting the culture with fluoroisocitrate (FIC) or a salt thereof.
地址 CL