Method for producing tooth

摘要

A method for producing a tooth having a desired length in one direction includes the steps of: placing a first cell aggregate and a second cell aggregate in the inside of a support while bringing the first and the second cell aggregates into close contact with each other; and culturing the first and the second cell aggregates in the inside of the support, in which the first cell aggregate is composed of one of mesenchymal cells or epithelial cells and the second cell aggregate is composed of the other, and the size of the tooth is controlled by adjusting the length of contact between the first cell aggregate and the second cell aggregate in one direction.

主权项

1. A method for producing a tooth, comprising: a step of arranging, in a support carrier, a column-shaped first cell aggregate comprising mesenchymal cells to be in contact with a column-shaped second cell aggregate comprising epithelial cells, wherein at least one of the mesenchymal cell and the epithelial cell is derived from a tooth germ, wherein said first cell aggregate and said second cell aggregate are cell masses, wherein a contact length between said column-shaped first cell aggregate and said column-shaped second cell aggregate is approximately within a range of plus and minus 25% of a desired length, wherein the contact length is measured in a direction that parallels an axis of said first or second column-shaped cell aggregate; and a step of culturing said first and second column-shaped cell aggregates inside the support carrier, thereby producing a tooth.