发明名称 Process for producing poly-γ-glutamic acid having high optical purity
摘要 It is an objective of the present invention to provide a process for efficiently producing poly-γ-glutamic acid having a high L-glutamic acid content and excellent quality. The process for producing poly-γ-glutamic acid according to the present invention is characterized in using a bacterium belonging to species Bacillus megaterium.
申请公布号 US8927236(B2) 申请公布日期 2015.01.06
申请号 US200712223067 申请日期 2007.01.31
申请人 Kochi University 发明人 Ashiuchi Makoto;Shimizu Kazuki
分类号 C12P13/14;C12R1/11;C12P21/02 主分类号 C12P13/14
代理机构 Bacon & Thomas, PLLC 代理人 Bacon & Thomas, PLLC
主权项 1. A process for producing poly-γ-glutamic acid, comprising: (a) preculturing Bacillus megaterium WH320 in a first culture medium having a sodium chloride concentration of 0.05% by mass or less; (b) cultivating the Bacillus megaterium WH320 in a second culture medium having a high sodium chloride concentration of 1.5% by mass or more; and (c) recovering from the second culture medium the poly-γ-glutamic acid released by the Bacillus megaterium WH320, wherein the poly-γ-glutamic acid comprises 90% or more L-glutamic acid.
地址 Kochi JP