发明名称 |
Methods of treating a tauopathy |
摘要 |
The present disclosure provides methods of treating a tauopathy, involving administering an anti-Tau antibody. The present disclosure also provides anti-Tau antibodies, and formulations comprising same, for use in the methods. |
申请公布号 |
US8926974(B2) |
申请公布日期 |
2015.01.06 |
申请号 |
US201314092539 |
申请日期 |
2013.11.27 |
申请人 |
iPierian, Inc. |
发明人 |
Griswold-Prenner Irene;Stagliano Nancy E.;Dang Vu;Hussain Sami;Bright Jessica Michelle |
分类号 |
A61K38/00;A61K39/00;A61K39/395;C07K16/18 |
主分类号 |
A61K38/00 |
代理机构 |
Nelson Mullins Riley & Scarborough LLP |
代理人 |
Nelson Mullins Riley & Scarborough LLP ;Remillard, Esq. Jane E.;Sloper, Esq. Jill Gorny |
主权项 |
1. A method of reducing the level of amyloid beta in a neuronal cell and/or an extracellular fluid in an individual, the method comprising administering to the individual:
a humanized antibody that binds an epitope within an extracellular tau (eTau) polypeptide in an amount effective to reduce the level of amyloid beta in the neuronal cell and/or the extracellular fluid in the individual, wherein said administering is effective to reduce the level of amyloid beta in the neuronal cell and/or the extracellular fluid in the individual. |
地址 |
South San Francisco CA US |