发明名称 Methods of treating a tauopathy
摘要 The present disclosure provides methods of treating a tauopathy, involving administering an anti-Tau antibody. The present disclosure also provides anti-Tau antibodies, and formulations comprising same, for use in the methods.
申请公布号 US8926974(B2) 申请公布日期 2015.01.06
申请号 US201314092539 申请日期 2013.11.27
申请人 iPierian, Inc. 发明人 Griswold-Prenner Irene;Stagliano Nancy E.;Dang Vu;Hussain Sami;Bright Jessica Michelle
分类号 A61K38/00;A61K39/00;A61K39/395;C07K16/18 主分类号 A61K38/00
代理机构 Nelson Mullins Riley & Scarborough LLP 代理人 Nelson Mullins Riley & Scarborough LLP ;Remillard, Esq. Jane E.;Sloper, Esq. Jill Gorny
主权项 1. A method of reducing the level of amyloid beta in a neuronal cell and/or an extracellular fluid in an individual, the method comprising administering to the individual: a humanized antibody that binds an epitope within an extracellular tau (eTau) polypeptide in an amount effective to reduce the level of amyloid beta in the neuronal cell and/or the extracellular fluid in the individual, wherein said administering is effective to reduce the level of amyloid beta in the neuronal cell and/or the extracellular fluid in the individual.
地址 South San Francisco CA US