| 发明名称 |
Substituerede isoquinolinoner og quinazolinoner |
| 摘要 |
<p>The invention relates to substituted nitrogen containing bicyclic heterocycles of the formula (I) wherein Z is CH2 or N-R4 and X, R1, R2, R4, R6, R7 and n are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and/or MDM4, or variants thereof.</p> |
| 申请公布号 |
DK2516009(T3) |
申请公布日期 |
2015.01.05 |
| 申请号 |
DK20100792944T |
申请日期 |
2010.12.21 |
| 申请人 |
NOVARTIS AG |
发明人 |
BERGHAUSEN, JOERG;BUSCHMANN, NICOLE;FURET, PASCAL;HERGOVICH LISZTWAN, JOANNA;HOLZER, PHILIPP;JACOBY, EDGAR;KALLEN, JOERG;MASUYA, KEIICHI;PISSOT SOLDERMANN, CAROLE;REN, HAIXIA;STUTZ, STEFAN;GESSIER, FRANÇOIS |
| 分类号 |
A61P35/00;A61K31/495;C07D217/24;C07D401/04;C07D401/10;C07D401/12;C07D401/14;C07D405/04;C07D405/12;C07D405/14;C07D409/12;C07D413/10;C07D413/12;C07D413/14;C07D417/12 |
主分类号 |
A61P35/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
