发明名称 |
Oligonukleotider til RNA-interferens samt biologiske anvendelser deraf |
摘要 |
<p>The invention relates to compositions comprising double-stranded oligonucleotides of identical or different sequences and/or length, said oligonucleotides having sequences 3′N1N2 . . . Ni-1Ni . . . Nj5′wherein—3′Ni . . . Nj5′is half of a double-stranded 19-28 mer oligonucleotide of sequence complementary to a target nucleic acid sequence present in a living cell, and—3′N1 . . . Ni-15′is a 3-50 mer overhang of sequence allowing oligomerisation of said double-stranded oligonucleotide. Compositions of transfection comprising said oligonucleotide compositions and there used for therapeutical application.</p> |
申请公布号 |
DK1888749(T3) |
申请公布日期 |
2015.01.05 |
申请号 |
DK20060754634T |
申请日期 |
2006.06.01 |
申请人 |
POLYPLUS TRANSFECTION |
发明人 |
BEHR, JEAN-PAUL;BOLCATO BELLEMIN, ANNE-LAURE;ERBACHER, PATRICK |
分类号 |
C12N15/113;A61K31/713;C12N15/11 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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