| 发明名称 |
Compuestos derivados de indolizina; procedimiento de preparación; composiciones farmacéuticas que los contienen y uso en el tratamiento del cancer. |
| 摘要 |
<p>Compounds of formula (I): wherein Ra, Rb, Rc, Rd, R1, R2, R3, R4, R5, X, Y and Het are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.</p> |
| 申请公布号 |
CL2014001829(A1) |
申请公布日期 |
2015.01.02 |
| 申请号 |
CL20140001829 |
申请日期 |
2014.07.10 |
| 申请人 |
LES LABORATOIRES SERVIER;VERNALIS (R&D) LTD |
发明人 |
LE DIGUARHER, THIERRY;CASARA, PATRICK;STARCK, JEROME-BENOIT;HENLIN, JEAN-MICHEL;DAVIDSON, JAMES EDWARD PAUL;MURRAY, JAMES BROOKE;GRAHAM, CHRISTOPHER JOHN;CHEN, I-JEN;GENESTE, OLIVIER;HICKMAN, JOHN;DEPIL, STEPHANE;LE TIRAN, ARNAUD;NYERGES, MIKLOS;DE NANTEUIL, GUILLAUME |
| 分类号 |
C07D471/00;A61K31/435;A61P35/00;C07D471/04;C07D487/04;C07D491/052 |
主分类号 |
C07D471/00 |
| 代理机构 |
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| 主权项 |
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