主权项 |
1. A single step process for the synthesis of 4-aryl substituted chromanes of compound of formula 2 comprising subjecting 3-aryloxy-1-phenylpropan-1-ol of formula 1 to gold(III) chloride-catalyzed intramolecular Friedel-Crafts reaction to obtain 4-aryl substituted chromanes wherein ‘Ar’ is selected from the group consisting of α-Naphthyl, 4-Methylphenyl, Phenyl, β-Naphthyl, 4-Chlorophenyl, 4-Bromophenyl, 4 -Fluorophenyl, 4-Cyanophenyl, Cesamoyl, 2-Methylphenyl, 2-Chlorophenyl, 2-Brormophenyl. |