BIOLOGICAL FLUIDS CONCENTRATION ASSEMBLY

摘要

A biological fluids concentration device, including a tube-in-tube assembly, is disclosed. The tube-in-tube assembly receives biologic fluids and may then be placed in the bucket of a centrifuge and spun to separate out the components of the biological fluid by their various densities. For example, whole blood may be centrifuged in the tube-in-tube assembly for separating into plasma, red blood cell component, and a buffy coat. A piston slideably and sealingly engages an inner tube of the tube-in-tube assembly, the inner tube fitting within an outer tube. A lid is designed to engage the top of the outer tube, which lid has an opening therein for receipt of a plunger. The plunger is adapted to move up and down with respect to the lid and the tubes, so as to sealingly, in a down position, and unsealingly, in an open position, engage the top of the inner tube of the tube-in-tube assembly.

主权项

1. A biological fluids concentration assembly comprising:
a tube-in-tube assembly defining a vertical axis and comprising a cylindrical outer tube and a cylindrical inner tube having inner walls, both tubes having open tops and both having cylinder bottoms, the open top of the inner cylinder being located below the open top of the outer cylinder; a piston for slidably and fluid sealingly engaging the inner walls of the inner tube below the open top; a lid having a body and a perimeter for engaging the open top of the outer tube, the lid having a bore located in the body thereof; a plunger capable of moving longitudinally with respect to the tube-in-tube assembly, the plunger having a body and a base, the plunger having a channel extending therethrough, the body dimensioned for moving longitudinally through the bore of the lid, the base configured to sealingly engage the open top of the inner tube, a channel of the plunger having an exterior opening that opens to the open top and an interior opening, opening to an interior of the tube-in-tube assembly; a piston for slidably and sealingly engaging the inner walls of the inner tube; and an assembly for engagement with the tube-in-tube assembly to move the piston towards the open top of the inner tube.