| 发明名称 |
DIFFERENTIATION INTO BROWN ADIPOCYTES |
| 摘要 |
The technology described herein is directed to methods and compositions relating to the differentiation and activity of brown adipocytes, and the therapeutic uses thereof. |
| 申请公布号 |
US2015004144(A1) |
申请公布日期 |
2015.01.01 |
| 申请号 |
US201214360097 |
申请日期 |
2012.11.28 |
| 申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
Cowan Chad;Schinzel Robert;Ahfeldt Tim;Lee YounKyoung |
| 分类号 |
G01N33/50 |
主分类号 |
G01N33/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for promoting the differentiation of cells into brown adipocytes comprising;
a) contacting a population of cells with at least one agent that increases the level or activity of PPARγ2 and C/EBPβ; and b) culturing the cells under conditions favorable for differentiation into brown adipocytes; wherein the method does not comprise contacting the cells with an agent which increases the level of PRDM16. |
| 地址 |
Boston MA US |
