发明名称 |
METHOD OF REPAIRING A TISSUE DEFECT USING GENIPIN CROSS-LINKED FIBRIN GELS |
摘要 |
The invention provides a genipin cross-linked fibrin gel. The ratio of genipin to fibrin in the gel ranges from about 0.1:1 to about 10:1 (genipin:fibrin). The gel can be hydrogel. The gel further contains proteins from the extracellular matrix that promote cell growth and density in and around the gel. Also provided is method for repairing tissue defects by administering the gel to site of tissue defect. |
申请公布号 |
US2015004138(A1) |
申请公布日期 |
2015.01.01 |
申请号 |
US201414483284 |
申请日期 |
2014.09.11 |
申请人 |
Icahn School of Medicine at Mount Sinai |
发明人 |
Iatridis James C.;Guterl Clare Canal |
分类号 |
A61K47/42;A61K9/00;A61K47/22;A61K38/39 |
主分类号 |
A61K47/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
New York NY US |