POLYMORPHIC FORM OF EZOGABINE AND PROCESS FOR THE PREPARATION THEREOF

摘要

A polymorphic form APO-I of Ezogabine, processes for the preparation thereof and pharmaceutical formulations comprising the polymorphic form APO-I are provided. The polymorphic form APO-I of Ezogabine of present invention offers an improved solubility profile. Ezogabine, also known as Retigabine, is indicated as adjunctive treatment of partial-onset seizures in patients aged 18 years and older.