MEDICAL DEVICE COMPRISING COLLAGEN-VI

摘要

A medical device intended for insertion into a living body comprises a non-biodegradable substrate having a tissue contact surface, wherein said tissue contact surface is at least partially coated with microfibrils of collagen VI. The inventors have found that the collagen VI coating provides antimicrobial properties against aerobic and anaerobic human pathogens. Furthermore, an unexpected synergistic effect between collagen VI and the innate immune system was obtained.