发明名称 BIARYL DERIVATIVES AS GPR120 AGONISTS
摘要 The present invention relates to biaryl derivatives of Formula 1, a method for preparing the same, a pharmaceutical composition comprising the same and use thereof. The biaryl derivatives of Formula 1 according to the present invention promote GLP-1 formation in the gastrointestinal tract and improve insulin resistance in the liver or in muscle due to anti-inflammatory action in macrophages, lipocytes, etc., and can accordingly be effectively used for preventing or treating diabetes, complications of diabetes, obesity, non-alcoholic fatty liver, steatohepatitis, osteoporosis or inflammation.
申请公布号 CA2912747(A1) 申请公布日期 2014.12.31
申请号 CA20142912747 申请日期 2014.06.26
申请人 LG LIFE SCIENCES LTD. 发明人 KIM, YOUNG KWAN;PARK, SANG YUN;JOO, HYUN WOO;CHOI, EUN SIL
分类号 C07D213/30;A61K31/4412;A61P3/00;A61P29/00 主分类号 C07D213/30
代理机构 代理人
主权项
地址