发明名称 |
Imidazopyridine or imidazopyrimidine derivatives as phosphodiesterase 10A inhibitors |
摘要 |
The invention is concerned with novel imidazopyridine derivatives of formula (I) wherein R1, R2, R3, R4, R5 and A are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit PDE10A and can be used for the treatment of various diseases, including central nervous system disorders such as Alzheimer's disease, Parkinson's disease, and schizophrenia. |
申请公布号 |
EP2480546(B1) |
申请公布日期 |
2014.12.31 |
申请号 |
EP20100760968 |
申请日期 |
2010.09.21 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
ALBERATI, DANIELA;ALVAREZ SÁNCHEZ, RUBÉN;BLEICHER, KONRAD;FLOHR, ALEXANDER;GROEBKE ZBINDEN, KATRIN;KOERNER, MATTHIAS;KUHN, BERND;PETERS, JENS-UWE;RUDOLPH, MARKUS |
分类号 |
C07D471/04;A61K31/437;C07D487/04 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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