发明名称 PHARMACEUTICAL COMPOSITIONS COMPRISING A HCV POLYMERASE INHIBITOR PRODRUG
摘要 <p>The present invention provides novel formulations of isobutyric acid (2R,3R,4R,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-4-fluoro-2-isobutyryloxymethyl-4-methyl-tetrahydro-furan-3-yl ester) and hydroxypropylcellulose that provide high bulk density, low particle size better suited for improved compression and flow, good compression, and fast dissolution profiles.</p>
申请公布号 SI2389164(T1) 申请公布日期 2014.12.31
申请号 SI20100030785T 申请日期 2010.01.11
申请人 F. HOFFMANN-LA ROCHE AG 发明人 CHATTERJI ASHISH;DESAI DIPEN;SANDHU HARPREET K.;SHAH NAVNIT HARGOVINDAS
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