发明名称 |
PROCESS FOR TUMOUR CHARACTERISTIC AND MARKER SET IDENTIFICATION, TUMOUR CLASSIFICATION AND MARKER SETS FOR CANCER |
摘要 |
A process to identify tumour characteristics involves obtaining three different marker sets each predictive of a characteristic of interest, obtaining a sample gene expression signals from tumour cells, adding a reporter to affect a change in the sample permitting assessment of a gene expression signal of interest in the tumour, combining the gene expression signals with the reporter, correlating the extracted gene expression signals to the three different marker sets, assigning a designation to the extracted gene expression signals according to the following rankings: if the correlation of all three predictive gene expression signal sets predict it to have characteristics of concern, it is designated a bad tumour; if the correlation of all three predictive gene expression signal sets predict it to lack characteristics of concern it is designated a good tumour; and, if the correlation of all three predictive gene expression signal sets do not provide the same predicted clinical outcome, the tumour is designated as “intermediate”; and, outputting said designation. |
申请公布号 |
EP2419533(A4) |
申请公布日期 |
2014.12.31 |
申请号 |
EP20100764018 |
申请日期 |
2010.04.16 |
申请人 |
NATIONAL RESEARCH COUNCIL OF CANADA |
发明人 |
WANG, EDWIN;LL, JIE;DENG, YINGHAI;LENFERLNK, ANNE EG;O'CONNOR-MCCOURT, MAUREEN, D.;PURISIMA, ENRICO |
分类号 |
C12Q1/68;C40B30/00;C40B30/02;C40B40/06;G01N33/68;G06F19/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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