| 摘要 |
An optical probe is provided comprising a probe element connected to a quencher by a cleavable linker; the probe element comprising a binding moiety, and a fluorophore being substantially fluorescently quenched by the quencher when the probe element is connected to the quencher by the cleavable linker; wherein the probe element is separated from the quencher when the cleavable linker is cleaved. Methods of using the probe are also provided. |
