发明名称 |
METHODS OF PRODUCING 7-CARBON CHEMICALS VIA PYRUVATE AND SUCCINATE SEMIALDEHYDE ALDOL CONDENSATION |
摘要 |
This document describes biochemical pathways for producing one or more of pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine and 1,7-heptanediol by forming one or two terminal functional groups, comprised of carboxyl, amine or hydroxyl groups, in a C7 aliphatic backbone substrate produced from succinate semialdehyde or pyruvate. These pathways, metabolic engineering and cultivation strategies described herein rely on the aldol condensation of succinate semialdehyde and pyruvate. |
申请公布号 |
WO2014105797(A3) |
申请公布日期 |
2014.12.31 |
申请号 |
WO2013US77430 |
申请日期 |
2013.12.23 |
申请人 |
INVISTA NORTH AMERICA S.A.R.L. |
发明人 |
BOTES, ADRIANA LEONORA;CONRADIE, ALEX VAN ECK;CHEN, CHANGLIN;PEARLMAN, PAUL S. |
分类号 |
C12P7/18;C12P7/42;C12P7/44;C12P13/00 |
主分类号 |
C12P7/18 |
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代理人 |
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