摘要 |
A method for crossmatching blood in which recipient serum is mixed with donor washed red blood cells and presence or absence of agglutination of red blood cells is recorded, wherein agglutination indicates an incompatible donor due to binding of antibodies in the recipient serum to the donor red blood cells, characterised in that the method comprises a step of incubating the mixed serum, donor cells and albumin at a preselected temperature greater than 37°C but not more than 50°C prior to assessment of agglutination. Preferably the temperature is between 39°C and 45°C. The method can be used for RhD (Du) testing in particular. Also claimed is a portable instrument for rapid blood typing or crossmatching of multiple samples using said method which comprises means for automatic control of sample incubation temperature and means to alert the operator upon incubation completion. |