发明名称 |
METHODS OF TREATING CHRONIC DISORDERS WITH COMPLEMENT INHIBITORS |
摘要 |
In some aspects, the invention provides methods of treating a subject in need of treatment for a chronic complement-mediated disorder. In some aspects, the invention provides methods of treating a subject in need of treatment for a Th17-associated disorder. In some aspects, the invention provides methods of treating a subject in need of treatment for a chronic respiratory system disorder. In some aspects, the invention provides methods of administering a complement inhibitor to a subject. In some embodiments, a method of treating a subject comprises administering multiple doses of a complement inhibitor to the subject according to a dosing schedule that leverages the prolonged effect of complement inhibition in chronic respiratory disorders. In some embodiments, a subject has chronic obstructive pulmonary disease. In some embodiments, a subject has asthma. |
申请公布号 |
EP2723361(A4) |
申请公布日期 |
2014.12.31 |
申请号 |
EP20120803380 |
申请日期 |
2012.06.22 |
申请人 |
APELLIS PHARMACEUTICALS, INC. |
发明人 |
FRANCOIS, CEDRIC;DESCHATELETS, PASCAL |
分类号 |
A61K38/10;A61K38/12;A61K39/395;A61P11/06;A61P27/00;G01N33/53;G01N33/68 |
主分类号 |
A61K38/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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