发明名称 |
CYCLIC PEPTIDES BINDING CXCR4 RECEPTOR AND RELATIVE MEDICAL AND DIAGNOSTIC USES |
摘要 |
<p>The present invention relates to the identification of new peptides and peptidomimetics which bind the CXCR4 receptor, capable of forming complexes with receptors for chemokines, in particular with CXCR4. The invention also relates to the use of these peptides for the treatment, prevention and diagnosis of diseases which involve chemokine receptors (i.e. neoplasias, metastases, HIV-1 virus infections), and also the mobilization of stem cells of hemopoietic precursors in the case of autologous transplants. Finally, the invention comprises pharmaceutical compositions and diagnostic kits comprising said peptides.</p> |
申请公布号 |
EP2528936(B9) |
申请公布日期 |
2014.12.31 |
申请号 |
EP20110710271 |
申请日期 |
2011.01.20 |
申请人 |
CONSIGLIO NAZIONALE DELLE RICERCHE;IRCCS- ISTITUTO NAZIONALE PER LO STUDIO E LA CURADEI TUMORI "FONDAZIONE GIOVANNI PASCALE" |
发明人 |
AMODEO, PIETRO;VITALE, ROSAMARIA;DE LUCA, STEFANIA;SCALA, STEFANIA;CASTELLO, GIUSEPPE;SIANI, ALFREDO |
分类号 |
C07K7/06;A61K38/12;C07K7/56 |
主分类号 |
C07K7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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