发明名称 |
ANTIBODIES BINDING TO PHOSPHORYLCHOLINE (PC) AND/OR PC CONJUGATES |
摘要 |
The present disclosure relates to an antibody or antibody fragment capable of binding to phosphorylcholine and/or a phosphorylcholine conjugate, wherein the antibody or antibody fragment comprises a variable heavy chain (VH) domain and/or a variable light chain (VL) domain, and wherein (a) the VH domain comprises complementarity determining regions (CDRs) selected from the group consisting of: a CDR1 sequence having identity to the sequence of SEQ ID NO: 7; a CDR2 sequence having identity to the sequence of SEQ ID NO: 8; and a CDR3 sequence having identity to the sequence of SEQ ID NO: 9 or 10; and/or (b) the VL domain comprises CDRs selected from the group consisting of: a CDR4 sequence having identity to the sequence of SEQ ID NO: 11; a CDR5 sequence having identity to the sequence of SEQ ID NO: 12; a CDR6 sequence having identity to the sequence of SEQ ID NO: 13. |
申请公布号 |
EP2741770(A4) |
申请公布日期 |
2014.12.31 |
申请号 |
EP20120821512 |
申请日期 |
2012.08.08 |
申请人 |
ATHERA BIOTECHNOLOGIES AB;DYAX CORP. |
发明人 |
PETTERSSON, KNUT;CAMBER, OLA;SEXTON, DAN;NIXON, ANDREW, E. |
分类号 |
A61K39/00;A61K39/395;C07K16/18;C07K16/44 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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