主权项 |
1. A cosmetic or dermatological preparation, wherein the preparation comprises one or more thiazoles of formula:in which
A=—NH(R1), R1 being selected from —C═O-alkyl (linear and branched), —C═O-alkenyl (linear and branched), —C═O—C1-C8-cycloalkyl, —C═O-aryl, —C═O-heteroaryl, —C═O-alkylaryl (linear and branched), and —C═O-alkylheteroaryl (linear and branched); X=C1-C8-cycloalkyl, C1-C24-alkylaryl (linear and branched), C1-C24-alkylheteroaryl (linear and branched), 4-hydroxyphenyl, 4-methoxyphenyl, 2,4-dihydroxyphenyl, 2,3-dihydroxyphenyl, 2,4-dimethoxyphenyl, or 2,3-dimethoxyphenyl; Y=H, C1-C24-alkyl (linear and branched), C1-C24-alkenyl (linear and branched), C1-C8-cycloalkyl, C1-C24-aryl, C1-C24-heteroaryl, C1-C24-alkylaryl (linear and branched), C1-C24-alkylheteroaryl (linear and branched), aryl, phenyl, 2,4-dihydroxyphenyl, 2,3-dihydroxyphenyl, 2,4-dimethoxyphenyl, 2,3-dimethoxyphenyl, —COO-alkyl, —COO-alkenyl, —COO-cycloalkyl, —COO-aryl, —COO-heteroaryl; and X and Y together may form an aromatic homo- or heterocyclic ring system having up to n ring-forming atoms, wherein n can have values from 5 to 8, and the respective ring system in turn may be substituted by up to n−1 substituents selected from one or more of alkyl groups, hydroxyl groups, carboxyl groups, amino groups, nitrile groups, sulfur-containing substituents, ester groups, and ether groups; and/or a thiazole of formula:the one or more thiazoles being present as free base or as cosmetically and dermatologically acceptable salt thereof. |