Pyrazole compounds, compositions and methods for treatment of degenerative diseases and disorders

摘要

Provided herein are compounds of the formula (I):;
as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.

主权项

1. The compound according to formula (I): wherein: R1 is pyridinyl; one of R2 or R2′ is hydrogen and the other is —CH2R3 or —CH2C(O)R3; and R3 unsubstituted phenyl or phenyl mono-, bi- or tri-substituted independently with alkoxy, or a pharmaceutically acceptable salt thereof.