| 发明名称 |
Pretreatment or post exposure treatment for exposure to a toxic substance by pulmonary delivery (inhaler) of a bioscavenger |
| 摘要 |
The present invention relates to a treatment by pulmonary delivery of a bioscavenger to animals as an effective antidote to prevent toxicity produced by exposure of an animal to nerve agents and other toxic substances. |
| 申请公布号 |
US8920824(B2) |
申请公布日期 |
2014.12.30 |
| 申请号 |
US201313769799 |
申请日期 |
2013.02.18 |
| 申请人 |
|
发明人 |
Rosenberg Yvonne |
| 分类号 |
A62D3/00;A62D3/02;A61K38/46;A01N25/00;A01N25/32;A61K31/215;A61K45/06;A61K9/00;A61K31/66 |
主分类号 |
A62D3/00 |
| 代理机构 |
MDIP LLC |
代理人 |
MDIP LLC |
| 主权项 |
1. A method of treating a human for exposure to a neurotoxin which comprises administering by inhalation to the lungs of said human an effective amount of a bioscavenger molecule that detoxifies said neurotoxin, wherein said neurotoxin is a nerve agent or a pesticide, and wherein said bioscavenger molecule is a paraoxonase, an organophosphate hydrolase, an organophosphorous acid anhydrolase or a parathion hydrolase which enzymatically cleaves said neurotoxin. |
| 地址 |
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