| 发明名称 | HCV vaccines and methods for using the same | ||
| 摘要 | Improved anti-HCV immunogens and nucleic acid molecules that encode them are disclosed. Immunogens disclosed include those having consensus HCV genotype 1a, including for example, NS4B, NS5A and NS5B. Pharmaceutical composition, recombinant vaccines comprising and live attenuated vaccines are disclosed as well methods of inducing an immune response in an individual against HCV are disclosed. | ||
| 申请公布号 | US8921536(B2) | 申请公布日期 | 2014.12.30 |
| 申请号 | US201113278160 | 申请日期 | 2011.10.20 |
| 申请人 | The Trustees of the University of Pennsylvania;Inovio Pharmaceuticals, Inc. | 发明人 | Weiner David B;Lang Krystle;Yan Jian;Draghia-Akli Ruxandra;Khan Amir S |
| 分类号 | C07H21/04;A61K48/00;A61K31/711;A61K39/29;A61K38/00;A61K39/00 | 主分类号 | C07H21/04 |
| 代理机构 | Riverside Law LLP | 代理人 | Riverside Law LLP |
| 主权项 | 1. A nucleic acid molecule comprising a coding sequence encoding one or more proteins selected from the group comprising: SEQ ID NO:2; or a protein that is 98% homologous to SEQ ID NO:2. | ||
| 地址 | Philadelphia PA US | ||