| 摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to novel amides of Lambert acids (13-E-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl) eudesmanolides) of formula (Ia-c), having antiulcer activity. In formula (Ia-c)where R=R=Me, X=H (Ia) or R=R=Me,R=R=CH, R=H, X=H (Ic). The compounds relate to class 3 moderately hazardous substances.EFFECT: compounds exhibit marked antiulcer activity on an indomethacin ulcer model.1 tbl, 6 ex |
