ONCOLYTIC ADENOVIRUS FOR TREATING CANCER, USING IT, AND PHARMACEUTICAL COMPOSITION CONTAINING IT

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: presented inventions refers to biotechnology, and particularly to oncology and concerns an oncolytic adenovirus, using it and a pharmaceutical composition containing this adenovirus. The characterized adenovirus contains a sequence intervening into its genome and coding hyaluronidase. The enzyme expression is controlled by a promoter active in animal's cells. The presented adenovirus can be used for preparing an agent for treating cancer and pre-cancer.EFFECT: invention enables providing higher effectiveness and selectiveness of the therapy.20 cl, 11 dwg, 10 ex