发明名称 Anticuerpos monoclonales neutralizantes de las exotoxinas tcda y/o tcdb de clostridium difficile; composición farmacéutica que los comprende; y uso para tratar infección por c. difficile.
摘要 <p>This present invention describes the derivation and selection of antibodies capable of neutralising the major exotoxins; TcdA and TcdB of Clostridium difficile. The invention also describes novel neutralisation and antigen binding properties of individual Mabs and mixtures thereof.</p>
申请公布号 CL2014000491(A1) 申请公布日期 2014.12.26
申请号 CL20140000491 申请日期 2014.02.27
申请人 UCB PHARMA S.A. 发明人 HUMPHREYS, DAVID PAUL;LIGHTWOOD, DANIEL JOHN;TYSON, KERRY LOUISE;KNIGHT, DAVID EDWARD ORMONDE;HERVÉ, KARINE JEANNINE MADELEINE;COMPSON, JOANNE ELIZABETH;PAGE, MATTHEW JON TIMOTHY;PAYNE, ANDREW CHARLES;FISHER, NICOLA LOUISE;MACKENZIE, BRENDON;COX, MATTHEW
分类号 C07K16/12;A61K39/40;A61P31/04 主分类号 C07K16/12
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