COMPOSITION FOR IMPROVING COGNITION AND MEMORY

摘要

The invention relates to a pharmacologically active combination, having utility in treating insomnia patients, which comprises: (a) at least one first active ingredient selected from melatonin, other melatonergic agents, melatonin agonists and melatonin antagonists; and (b) at least one second active ingredient selected from nicotine and nicotine receptor agonists; to use of a medicament containing component (a) with or without component (b) for alleviation of at least one adverse effect which occurs in a patient in the course of nicotine replacement therapy, or otherwise, selected from impairment of the quality of sleep, impairment of cognition and impairment of memory, as well as to a kit having utility in treating insomnia patients, which comprises components (a) and (b) in unit dosage form.

主权项

1. A pharmacologically active combination comprising:
(a) a first active ingredient selected from melatonin or a melatonin agonist; and (b) at least one second active ingredient selected from nicotine or a nicotine receptor agonist; wherein said first active ingredient is provided in controlled, sustained or prolonged release form and said pharmacologically active combination contains said first and second active ingredients in an amount effective for treatment of cognitive dysfunction and sleep impairment.