发明名称 |
SCAFFOLDS FORMED FROM POLYMER-PROTEIN CONJUGATES, METHODS OF GENERATING SAME AND USES THEREOF |
摘要 |
Conjugates are provided herein which comprise a protein attached to at least two polymeric moieties, at least one of which exhibits reverse thermal gelation. The conjugates are suitable for being cross-linked by non-covalent and/or covalent cross-linking. Compositions-of-matter comprising cross-linked conjugates are provided herein, as well as processes for producing same. Methods of controlling a physical property of compositions-of-matter are also provided herein. The conjugates and compositions-of-matter may be used for various applications, such as cell growth, tissue formation, and treatment of disorders characterized by tissue damage or loss, as described herein. |
申请公布号 |
US2014377209(A1) |
申请公布日期 |
2014.12.25 |
申请号 |
US201414480778 |
申请日期 |
2014.09.09 |
申请人 |
Regentis Biomaterials Ltd. |
发明人 |
SELIKTAR Dror;Shachaf Yonatan |
分类号 |
A61K47/48;A61K38/18;A61K38/36;A61K35/12 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
1. A conjugate comprising a polypeptide having attached thereto at least two polymeric moieties, at least one of said polymeric moieties exhibiting a reverse thermal gelation. |
地址 |
Or-Akiva IL |