发明名称 USE OF 2,5-DIHYDROXYBENZENESULFONIC ACID IN PRODUCTION OF MEDICAMENTS FOR TREATING ANGIODEPENDENT DISEASES SUCH AS CANCER AND PSORIASIS
摘要 PROBLEM TO BE SOLVED: To provide the production of medicaments for treating angiodependent diseases.SOLUTION: This invention relates to the use of 2,5-dihydroxybenzenesulfonic acid in the production of medicaments for treating angiodependent diseases. More specifically, this invention relates to the use of the compound and, in particular, calcium and potassium salts thereof, for the treatment of two angiodependent diseases, which present a reduction in the apoptosis, namely cancer and psoriasis. This invention also relates to antiproliferative, antimigratory, antiangiogenic and apoptosis capacity of the family of compounds in non-quiescent cells. In addition, this invention relates to the potentiating effect of the compounds on known cytostatic medicines in the treatment of tumors and, specifically, on gliomas. Additionally, this invention relates to the therapeutic efficacy of the compounds, based on the combined anti-proliferative, antiangiogenic and apoptosis capacities thereof, in the treatment of chronic psoriatic plaques.
申请公布号 JP2014240445(A) 申请公布日期 2014.12.25
申请号 JP20140205125 申请日期 2014.10.03
申请人 AMDERMA PHARMACEUTICALS LLC 发明人 CUEVAS SANCHEZ PEDRO;ROMERO GARRIDO ANTONIO;PUERTO ROSA MARIA LOZANO;GALLEGO GUILLERMO GIMENEZ;LOPEZ SERAFIN VALVERDE
分类号 A61K31/185;A61K31/255;A61P17/06;A61P35/00;A61P43/00 主分类号 A61K31/185
代理机构 代理人
主权项
地址