ASSAY CARTRIDGES AND METHODS OF USING THE SAME

摘要

Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.

主权项

1. A method of conducting an electrochemiluminescence measurement, said method comprising the steps of:
measuring the impedance between two electrodes in a measurement chamber to detect the presence of air bubbles, said measurement using electrical potentials that are insufficient for generating electrochemiluminescence at said electrodes; and inducing electrochemiluminescence at one of said two electrodes.