| 摘要 |
PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for treating hyperproliferative diseases, such as cancer, inflammatory diseases and viral and bacterial infections.SOLUTION: Pharmaceutical compositions comprise specific nitrile derivatives represented by the formula I. [Z is S; n and m are integers from 0 to 8; Rto Rare H, -CH2-cyclohexyl, C1-6 alkyl, C2-6 alkenyl, or C2-6 alkynyl; W is absent or is -CHR-CHR-, -CR=R-, or -C≡C-; Rand Rare -CH-cyclohexyl, Calkyl, Calkenyl, Calkynyl, or Calkyl ether; and R1 and R2 may form a five or more membered heterocycle including nitrogen.] |
