发明名称 |
TUSC2 THERAPIES |
摘要 |
A method for predicting a subject's response to a TUSC2 therapy is provided. In particular, a subject's response is predicted based on the proportion of cancers cells that are apoptotic. Also provided is a method of treating a subject previously predicted to have a favorable response with a TUSC2 therapy. Methods for treating cancer by administration of a TUSC2 therapeutic in conjunction with an EGFR inhibitor and/or a protein kinase inhibitor are also disclosed. Kits and reagents for use in TUSC2 therapy are provided. |
申请公布号 |
US2014377339(A1) |
申请公布日期 |
2014.12.25 |
申请号 |
US201414480341 |
申请日期 |
2014.09.08 |
申请人 |
Board of Regents, The University of Texas System |
发明人 |
ROTH Jack;STEWART David;LU Charles;WISTUBA Ignacio I.;YAN Shaoyu;NUNEZ Maria I. |
分类号 |
A61K9/127;A61K31/517;C07K14/47;A61K38/17 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Austin TX US |