| 发明名称 |
USE OF 2-DEOXY-D-GLUCOSE TO SENSITIZE CANCER CELLS TO AN AGENT THAT ACTIVATES THE EXTRINSIC APOPTOTIC PATHWAY |
| 摘要 |
Methods for sensitizing a solid tumor cell to an agent that activates the extrinsic apoptotic pathway and treating a solid tumor using a combination of 2-deoxy-D-glucose and an agent that activates the extrinsic apoptotic pathway are described. |
| 申请公布号 |
US2014377274(A1) |
申请公布日期 |
2014.12.25 |
| 申请号 |
US201414314342 |
申请日期 |
2014.06.25 |
| 申请人 |
The Board of Trustees of the University of Illinois |
发明人 |
Maker Ajay |
| 分类号 |
A61K39/395;A61K45/06;A61K31/282;A61K31/7004 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for sensitizing a solid tumor cell to an agent that activates the extrinsic apoptotic pathway comprising contacting a solid tumor cell with an effective amount of 2-deoxy-D-glucose and an agent that activates the extrinsic apoptotic pathway thereby sensitizing the solid tumor cell to an agent that activates the extrinsic apoptotic pathway. |
| 地址 |
Urbana IL US |
