| 摘要 |
The present invention concerns a device for analyzing biological parameters from a sample (6) comprising (i) first transferring means (5, 20, 25), (ii) first preparing means (7), (iii) means for measuring cellular components (8), (iv) second preparing means (10, 11, 22, 23, 24) capable of carrying out, on a sample from the first preparing means (7), at least one dilution with an assay reagent (R3) comprising particles functionalized at the surface with at least one ligand specific to at least one analyte of interest, (v) immunodetection measurement means (30, 31) capable of assaying at least one analyte of interest by measuring the aggregation of functionalized particles, said device further comprising (i) second transferring means (4, 21, 22, 26) at least partially separate from the first transferring means (5, 20, 25) and (ii) means for applying a magnetic field (28) capable of causing, by magnetic interaction, an acceleration of the aggregation of said functionalized particles, which comprise magnetic colloidal particles. The invention also concerns a method implemented in said device. |
| 主权项 |
1. A device for analyzing biological parameters using a biological sample (6), comprising:
first transferring means (5, 20, 25) capable of at least partially transferring said biological sample (6) to first preparing means (7), first preparing means (7) capable of carrying out at least one dilution of said biological sample (6) with at least one diluent and/or one reagent, second preparing means (10, 11, 22, 23, 24) capable of carrying out, on a first sample from the first preparing means (7), at least one dilution with an assay reagent (R3) comprising particles functionalized at the surface with at least one ligand specific for at least one analyte of interest, immunodetection measurement means (30, 31) capable of assaying, on a sample from the second preparing means (10, 11, 22, 23, 24), at least one analyte of interest by measuring the degree of aggregation of functionalized particles in a measuring cuvette (9),characterized in that it also comprises:
second transferring means (4, 21, 22, 26) at least partially separate from the first transferring means (5, 20, 25) and capable of taking said first sample diluted beforehand in the first preparing means (7), and of transferring it to the second preparing means (10, 11, 22, 23, 24), and means for applying a magnetic field (28) in said measuring cuvette (9), capable of causing, by magnetic interaction, an acceleration of the aggregation of said functionalized particles, which comprise magnetic colloidal particles. |
